National Institute of Child Health and Human Development
Maternal-Fetal Medicine Units Network



Publications and Presentations
Randomized Placebo-Controlled Trial of
Antenatal Corticosteroid Regimens


  • Wapner RJ, Sorokin Y, Thom EA, Johnson F, Dudley D, Spong CY, Peaceman AM, Leveno KJ, Harper M, Caritis SN, Miodovnik M, Mercer BM, Thorp JM, Moawad AH, O'Sullivan MJ, Ramin SM, Carpenter MW, Rouse DJ, Sibai BM, Gabbe SG, for the National Institute of Child Health and Human Development Maternal Fetal Medicine Units Network. Single vs. weekly courses of antenatal corticosteroids: evaluation of safety and efficacy. American Journal of Obstetrics and Gynecology, 195:633-642, 2006.
  • Sawady J, Mercer BM, Wapner RJ, Zhao Y, Sorokin Y, Johnson F, Dudley DJ, Spong CY, Peaceman AM, Leveno KJ, Harper M, Caritis SN, Miodovnik M, Thorp JM, Ramin SM, Carpenter MW, Rouse DJ for the National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Beneficial effects of antenatal repeated steroids study: impact of repeated doses of antenatal corticosteroids on placental growth and histologic findings. American Journal of Obstetrics and Gynecology, 197:281.e1-281.e8, 2007.
  • Wapner RJ, Sorokin Y, Mele L, Johnson F, Dudley DJ, Spong CY, Peaceman AM, Leveno KJ, Malone F, Caritis SN, Mercer BM, Harper M, Rouse DJ for the National Institute of Child Health and Development Maternal-Fetal Medicine Units Network. Long term outcomes of a randomized trial of repeat antenatal corticosteroids. New England Journal of Medicine, 357:1190-1198, 2007.
  • Carroll MA, Vidaeff AC, Mele L, Wapner RJ, Mercer BM, Peaceman AM, Sorokin Y, Dudley DJ, Spong CY, Leveno KJ, Harper M, Caritis SN, Miodovnik M, Thorp JM, Moawad AH, O'Sullivan MJ, Carpenter MW, Rouse DJ, Sibai BM, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network. Bone Metabolism in Pregnant Women Exposed to Single Compared With Multiple Courses of Corticosteroids. Obstetrics and Gynecology, 111:1352-1358, 2008.
  • Presentations

    1. Wapner R, for the NICHD MFMU Network. A randomized trial of single vs. weekly courses of corticosteroids. Presented at the 24th Annual Meeting of the Society for the Maternal Fetal Medicine, New Orleans, LA, February 2004.


    2. Sorokin Y. for the NICHD MFMU Network. Effect of maternal BMI, number of courses and timing of antenatal corticosteroids: Association with neonatal anthropometric measurements. Presented at the 25th Annual Meeting of the Society for Maternal-Fetal Medicine, Reno, NV, February 2005.


    3. Church M. for the NICHD MFMU Network. Auditory brainstem responses (ABRs) in neonates exposed to repeated courses of antenatal corticosteroids. Presented at the 25th Annual Meeting of the Society for Maternal-Fetal Medicine, Reno, NV, February 2005.


    4. Wapner RJ for the NICHD MFMU Network. Maternal and fetal adrenal function following single and repeat courses of antenatal corticosteroids (ACS). Presented at the 26th Annual Meeting of the Society for Maternal-Fetal Medicine, Miami Beach, FL, January 2006.


    5. Sorokin Y for the NICHD MFMU Network. Elevated maternal serum IL-6 is associated with preterm delivery <32 weeks and subsequent neonatal intraventricular hemorrhage. Presented at the 26th Annual Meeting of the Society for Maternal-Fetal Medicine, Miami Beach, FL, January 2006.


    6. Carroll, MA and Vidaeff, AC for the NICHD MFMU Network. Bone metabolism in pregnant women exposed to single versus multiple courses of corticosteroids. Presented at the Annual Meeting of the Society for Gynecological Investigation, Toronto, Canada, March 2006.


    7. Wapner, R for the NICHD MFMU Network. Long term follow-up of infants receiving single vs repeat courses of antenatal corticosteroids (ACS) from the MFMU RCT. Presented at the 27th Annual Meeting of the Society for Maternal-Fetal Medicine, San Francisco, CA, February 2007.


    8. Sawady, J and Mercer, B for the NICHD MFMU Network. Impact of Repeated Doses of Antenatal Corticosteroids on Placental Growth and Histology. Presented at the 27th Annual Meeting of the Society for Maternal-Fetal Medicine, San Francisco, CA, February 2007.


    9. Fonseca, L for the NICHD MFMU Network. Bone metabolism in the fetuses of pregnant women exposed to single and multiple courses of corticosteroids. Presented at the 54th Annual Scientific Meeting for Society of Gynecologic Investigation, Reno, NV, March 2007.




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