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EFFECTS OF MATERNAL LIFESTYLES ON INFANT OUTCOMES (EMLI)

Principal Investigator:  Raymond P. Bain, Ph.D.
Co-Investigator:  Joel I. Verter, Ph.D.

 
The Effects of Maternal Lifestyles on Infant Outcomes study was a cross-sectional screening and prospective cohort study to evaluate the relationship between maternal use of cocaine and/or opiates during pregnancy and the incidence of acute neonatal complications and long-term neurodevelopmental outcome of both premature and full-term infants. Based on results of screening over 19,000 mothers for in-utero exposure to cocaine/opiate by meconium and maternal self-report in 4 clinical centers, 658 infants, and their mothers, positive for in-utero exposure and 742 matched controls, have been enrolled in a 3-year neurobehavioral, neurodevelopmental and environmental follow-up evaluation. The EMLI study was sponsored by the National Institute of Child Health and Development (NICHD), National Institute on Drug Abuse & Addiction (NIDA), Center for Substance Abuse Treatment (CSAT) and the U.S. Department of Health and Human Services Administration for Children and Families(ACYF).

NIH/NICHD Cooperative Agreement 5-U01-HD-19897, 1992-1998.)