Collaborative Study of the Treatment of Lactic Acidosis with
Dichloroacetate
Principal Investigator: Elizabeth C. Wright, Ph.D.
randomized, controlled, multicenter study of 252 patients at 8 centers to evaluate the effectiveness of DCA in the treatment of acute lactic acidosis. The study showed that DCA had some beneficial effects on the acute biochemical imbalance but failed to improve survival (NEJM, 1992). NIDDK Grant R01-AM-35448, 1986-1992
randomized, controlled, multicenter study of 252 patients at 8 centers to evaluate the effectiveness of DCA in the treatment of acute lactic acidosis. The study showed that DCA had some beneficial effects on the acute biochemical imbalance but failed to improve survival (NEJM, 1992). NIDDK Grant R01-AM-35448, 1986-1992